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In particular, the assumption of independent realizations can be problematic for spatial or temporal data, although in principle, adjustments for such difficulties sometimes can be made.
In principle, adjustments could be made to take account of the different impact factors of journals in different research fields.
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Although this is a randomised controlled trial and therefore in principle adjustment for other variables is not needed, we did perform analyses where adjustments were made for study center and for those factors that were imbalanced at baseline (gender, chest pain, hypertension).
Although being less reliant on banking might be good for the U.K. in principle, the adjustment would be brutal.
The principle for adjustment is summarized as follows: (1) Calculate the vector of unknown model parameters ({mathbf{m}}^{k + 1}).
It is recognised that markets for many (if not most) goods and services do not accord with these principles, so adjustments are made.
Differences in the available data in relation to ascertainment of DR3 status necessitated several analyses, and the results of the regression coefficients for these analyses are depicted in Table 3. aAnalysis performed using principle components adjustment for possible ancestry differences.
Second, although it might sound good in principle — these structural adjustment loans — all the empirical evidence is that aid is not successful in changing behavior.
These results show that under the principle of minimal flux adjustment, when adaptation occurs with growth variation, the network presents global reorganization of the flux pattern while, when adaptation occurs keeping growth at its maximum value, large changes in only a small proportion of the fluxes take place.
Consequently, directly merging genotypes from either ancestrally divergent populations or those that have undergone varying degrees of admixture using traditional association testing frameworks (such as global ancestry adjustment using principle component or multi-dimensional scaling) to adjust for population substructure does not sufficiently control for the risk of confounding [ 77, 81, 89, 90].
Mr Osborne explained to committee chairman Andrew Tyrie: "The no detriment principle is around the adjustments to the block grant connected with the loss or additional tax revenues that come from the first round effects and potentially behavioural effects.
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