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But while the world's biggest economies have adopted those goals in principle, achieving them in practice has proved difficult.
The really sharp operator, experience insists, works by the "less is more" principle, achieving her effects by stealth, subtlety and quiet subterfuge.
Since TADs recruit transcriptional machinery through direct binding interactions with coactivator proteins, varying these domains changes the activation potential of each individual TF, thereby in principle achieving vertical extension (adjusting the high-end saturation limit of the activation response curve).
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A sophisticated approach for nonclassical characteristics of superposition state is in principle achieved by taking advantage of WDF[21, 24].
For example, both Poincaré and Carnap seem to regard conventional stipulation as something that a lone cognitive agent could in principle achieve.
Identification of metabolites can be in principle achieved using high resolution multistage mass spectrometry (MSn) because it provides a feature rich fingerprint of the precursor structure.
Alternative mutagenesis strategies use temporary plasmid or cassette insertions and can in principle achieve equally flexible mutation designs, but design of suitable counter-selected markers can be complex.
We have developed a capacitance detector which is able to detect displacements of the order of 0.1 nm.We show that sensitivities of the order of 0.5×10−11 A m2 can be in principle achieved.
However, concentrative uptake in to a compartment could in principle achieve the necessary concentrations (Fig. 9).
Our genetic method has several advantages compared to other methods, such as viral transduction or in utero electroporation, which can in principle achieve similar labeling of both the entire neuron and presynaptic terminals.
By linking a cytotoxic payload to an antibody that specifically recognizes antigens expressed on target cells, one could, in principle, achieve potent efficacy without unwanted side effects.
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CEO of Professional Science Editing for Scientists @ prosciediting.com