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Commissioner Perine cited Mayor Rudolph W. Giuliani's statements that cost reduction principally requires eliminating organized crime in the construction industry, easing zoning restrictions and speeding up the permitting process.
Also, accumulation of GNDs principally requires pre-straining.
The Rio-BHP joint venture principally requires approvals from relevant anti-trust regulators in Australia, USA, South Africa and the E.U.
Management principally requires lifestyle (i.e. behavioural) changes.
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Since these approaches were direct adoptions of Alamouti's scheme and its corresponding generalization, they principally require perfect orthogonality among the relay signals.
The identification of monoclonal protein production is not proof of multiple myeloma, but indicates that further investigations are required (principally a bone marrow biopsy and skeletal survey).
Other authors were unable to show function heterologous expression of alkB genes in Pseudomonas or E. coli expression system, principally because the functional expression requires proper synthesis, correct folding, and proper assembly, and these are not always ensured for rhodococcal proteins (Whyte et al., [2002]).
However, most, if not all of these provide only clinical validity, with little or no effort to produce high level evidence for clinical utility, principally because to do so requires careful planning, hard work, extensive time, and substantial cost.
Whether there are differences in the magnitude of health effects between PM2.5 and traffic air pollution exposures and the underlying pollutant constituents principally responsible for promoting diabetes mortality requires further study.
To prevent this decay requires time-consuming maintenance behaviors, principally communication and joint activities (Cummings et al. 2006; Oswald and Clark 2003).
As such, this system requires the provision of input; principally, but not exclusively, via the retino-geniculate pathway to multiple early regions for parallel processing and feed-forward to higher areas in occipital cortex and beyond.
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