Sentence examples for principally intact from inspiring English sources

Although those babies are born at a time with a principally intact nephrogenic zone and active niches, a high proportion of them suffers on impairment of nephrogenesis resulting in oligonephropathy, formation of atypical glomeruli, and immaturity of parenchyma.

Importantly, even if vagal tone is reduced, the ability to stimulate the vagal nerve and induce bradycardia remains principally intact [ 5], suggesting that pentobarbital's vagolytic effects are centrally mediated and do not interfere with efferent vagal nerve stimulation.

The observation that the network of known tip cell markers and their targets is principally intact and in fact upregulated rather than downregulated may be a reflection of the more immature vessel plexus in Nrp1 null mutants.

Thus, in our previous work we tested this idea principally in intact purified, bovine adrenal medulla chromaffin granules and showed the presence of the C-terminus of PC1 on the outside of these granules.

In contrast, in cells with abundant and intact CK1ε, Wnt5a principally stimulates other noncanonical signaling pathways that involve CK1, such as the Wnt/CK1ε/Rap1 [ 32] and Wnt/Yes-Cdc42-CK1α [ 33] pathways, and promotes cell adhesion [ 33].

The intact endothelium promotes vasodilatation principally via the release of nitric oxide, originally known as endothelium-derived relaxing factor.

Attempts to overcome these problems have led to two retroviral vector designs of principally opposite character: replication-competent vectors transducing largely intact genomes and genome-free vectors.

For example, the insert shown in Fig.  3, of chr22 into chr 8 consisted principally of chr22 sequence, from 29066229 29066424, 3' to the intact L1 that ends at 29065303, followed by 37bp of polyA (Fig.  3).

Having battled to half-time with their resolve intact, Scotland created an early second-half chance, principally through great desire shown by Charlie Adam and when the ball broke to Steven Naismith, he curled it beautifully past Vladimir Stojkovic, only for his celebrations to be brought to an immediate halt by the assistant referee's offside flag.

Transcutaneous electrical nerve stimulation (TENS) is the delivery of pulsed low voltage electrical currents across the intact surface of the skin to stimulate peripheral nerves principally for pain relief [4].

Equally, however, his tendency to pillage and plagiarise his own work – principally Gladiator's plot (itself borrowed from The Fall Of The Roman Empire, Ben-Hur and The Ten Commandments) – remains intact.