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Since macrophages and granulocytes descend from a common progenitor (i.e., GMP), their early differentiation steps from HSCs or PSCs toward the myeloid lineage are principally guided by the same molecular cues.
The decision of conducting the study retrospectively in a secondary care setting was principally guided by the low prevalence of IgAD that could eventually increase the length of the study.
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The division into an M pathway, concerned principally with guiding action, and a P pathway, concerned with the identities of objects, is believed to be preserved through the various stages of cortical processing.
By Jeffrey Toobin Burris is a conventional politician, guided principally by cautious self-interest.
Since the A.K.P. came to power, more than a decade ago, Zaman's ties with Gülen have alienated some people in the Turkish media, who consider the company to be guided principally by the imam.
I chose to study astrophysics at university on something of a whim, my decision being guided principally by the alphabetical arrangement of the UCCA handbook, rather than the fine structure or content of the course itself.
With respect to principles, he is guided principally by his ego (more on that below).
Like so many things in life these days, I'm guided principally by the photographs I've accumulated from that time.
These findings further support our conclusion that landings are guided principally by visually contrasting features.
Model development was guided principally by diagnostic plots and CIs of the mixed-effects parameters using the standard error of the estimates (derived via the covariance option in NONMEM), with the minimum objective function value as a secondary measure.
Additionally, these results suggest that, while N-terminal signals principally direct export from the parasite, the final destination of exported proteins is guided by the C-terminus.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com