To date the involvement of α-crystallin, a molecular chaperone for β- and γ-crystallin, has principally been considered in senile cataract development [ 1, 2], the decrease in the chaperone ability of α-crystallin with age being implicated.
Given that most of the studies we found were not principally concerned with social networks or peer support, however, the findings of our efforts need to be considered principally as an agenda for future research.
Once understood, principally every condition impacting this mechanism could be considered as contributing to AD and effective therapeutic options targeting this mechanism could be rationalised for treating AD.
While both types of theory can contribute principally to an improvement of practice, their different aims and character should be considered in the selection of a normative background.
LONG gone are the days when children's toys were principally powered by mainsprings and imagination, when a doll capable of uttering only "Mama" would be considered downright chatty.
Two principally different applications are considered, (1) effects monitoring with biological components as targets for bioeffective substances, among them endocrine disruptors; and (2) immunochemical analysis employing antibodies as binding proteins for a wide variety of analytes such as pesticides.
"Intelligence has always been considered principally an immutable inherited trait," said Susanne M. Jaeggi, a postdoctoral fellow in psychology at the University of Michigan and a co-author of the paper.
Based on the analysis of the characteristic hysteretic behavior of concrete, the residual deformation in tension was considered principally due to the incomplete closure of the opening cracks.
Here they are principally represented by what is considered to be a bipolar species, Limacina helicina (Phipps 1774) (Figure 1a).
The model which best accounted for this was that where mutations affecting exons 45 to 50 (the 6½ exons comprising the noncoding 5'UTR of Dp140) were considered principally as coding exon mutations whose effect is restricted to Dp260 and Dp427.
