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In this study, we show that neural stem cells (NSCs) and neuronal precursor cells are the principal target cells for MCMV in the developing brain.
In this study we found that NSCs and neuronal precursor cells are the principal target cells for MCMV within the developing brain.
The principal target cells for EBV infection are human primary B lymphocytes, but the virus can also infect other lymphocytes and epithelial cells [2], [3], [4], [5], [6].
The principal target cells for JEV are localized in CNS, including neurons and astrocytes [ 90].
The principal target cells of HIV in the human body are CD4+ T lymphocytes, macrophages, and dendritic cells.
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Since the principal dengue target cells are monocytic cells including monocyte, macrophage and dendritic cells [36] [38] and HIV infects macrophage and CD4+ T cells, it may be expected that dengue and HIV infections directly stimulate relevant human cells to make IFNα, but not IFNβ.
Our results show a decreased AP threshold, which would seem to be a principal target for cell-wide synaptic gain modulation.
From this study, VRE was shown to resist DAP-elicited cell membrane damage by diverting the antibiotic away from its principal target to other distinct cell membrane regions.
The results implicate self-repair as the principal target of these heart-derived cells in the treatment of heart disease, until persistent engraftment of mechanically active and well-integrated cardiomyocytes is achieved.
Although the transgene expression in principal targets all AT2 cells only a subset of them responded to expression of the C-RAF BXB with the formation of tumors [7].
IL-6 is a cytokine of innate immunity, its principal targets being the liver cells, the β cells and the naïve T cells [ 25].
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