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Historical comparisons between clinical trial are hazardous because there is considerable variability between study population, schedule and methodology of response evaluation, although with these considerations in mind the median survival for GEM alone, on GOIRC trial, was better than the principal studies with GEM alone (7 vs 5.7 months).
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Studies were classified as principal, or subsidiary where cases overlapped with principal studies.
The following year we experimentally replaced male lizards on Kidd cay, our principal study site, with individuals from an adjacent site on Great Exuma [ 14].
One potential limitation of our study is that the principal studies quantifying the risk of GBS with influenza illness ascertained cases of influenza in different ways.
d RRs from principal studies.
The Open Door intervention was taught during a two-day training provided by the principal study investigator (JAS) with weekly supervision provided for the first 6 months followed by monthly supervision thereafter.
This outcome, compared with the principal study outcomes, will provide insight into the accuracy with which physicians' discern their own prescribing practices.
Simon's optimal two-stage design for phase II clinical trial was used to calculate the sample size, with the principal study end point being the pCR rate.
Studies with principal investigators with no or invalid e-mail address were more likely to be sponsored by the National Institutes of Health, to be in the field of oncology, and more likely to study a drug.
In the previous studies with principal component analysis and factor analysis of WCST scores in patients with schizophrenia, categories complete (CC; an indicator examining numbers of categories achieved in the same way as CA), PE (an indicator examining perseveration in the same way as PEM and PEN) and TE mainly constituted one factor.
During the study meeting with the principal, the study aims, proposed methods, study procedures were discussed.
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