Sentence examples for principal side effects from inspiring English sources

But 2 years ago, a team led by cancer biologist Richard Kolesnick and radiologist Zvi Fuks of Memorial Sloan-Kettering Cancer Center in New York City showed that one of the principal side effects of radiation therapy, damage to the gastrointestinal tract, occurs because the radiation triggers apoptosis, a form of cell suicide, in the cells of the small blood vessels of the tract.

The principal side effects of metformin occur in the gastrointestinal tract (mostly diarrhoea); these can be minimised by starting metformin at a low dose and increasing the dose cautiously and infrequently cause treatment discontinuation [ 57].

Overall, IDegLira offers simple titration of two efficacious therapies in a single daily injection while mitigating the principal side effects of basal insulin (hypoglycemia and weight gain) and GLP-1RA (nausea) when given alone [ 55, 56].

The principal side effects are osteoporosis resulting in increased incidence of bone fractures, hypercholesterolemia with no significant increase in cardiovascular risk, and musculoskeletal events such as arthralgia and myalgia [ 2].

In both Aleppo and Mosul, tactics such as seizing territory and cutting off supply lines are spurred by military aims — but a principal side effect is leaving civilians homeless and hungry.

Haematological toxicity was the principal side effect.

The principal side effect was arthralgia in 14 (12%) patients at 28 days and 33 (29%) patients over the whole study.

In six patients, the principal side effect was rib fractures that occurred with a median delay of 12 months after the treatment.

The protocol for glucose control in group 2 has been carefully designed to achieve tight glucose control whilst minimizing the risk of hypoglycaemia, the principal side effect of insulin therapy.

The most common type of this kind of PK/PD model is one in which a summary measure of exposure, such as AUC, is related to the principal side effect of the treatment, in this case haematological toxicity, for which singly measured nadir counts are usually employed.

The principal side-effects were oral mucositis (12/30 patients), nausea (8/30 patients) and transient diarrhoea (4/30 patients), and initial constitutional symptoms due to alpha 2b interferon.