Sentence examples for principal regulators of from inspiring English sources

Of these, the principal regulators of EMT are transcription factors classified into 3 families: SNAIL, TWIST, and zinc-finger E-box-binding (ZEB).

The principal regulators of the system are t-PA and its primary inhibitor PAI-1.

However, as the principal regulators of vascular permeability, endothelial cells are likely to be involved in systemic increases in permeability.

One of the principal regulators of mitogenesis in vascular smooth muscle cells is platelet-derived growth factor-BB (PDGF-BB).

The iron response elements or iron-responsive elements (IRP1 and IRP2) are the principal regulators of cellular Fe homeostasis in vertebrates.

This is again consistent with the physiologic understanding that the vitamin D hormone system and parathyroid hormone are the principal regulators of serum concentrations of calcium [ 21].

Interestingly, PXC1 has been identified in the repertoire of genes regulated by SND2, which is an indirect target of a principal regulator of fiber secondary cell wall formation, SND1 [ 38, 39].

Modulation of the mammalian target of rapamycin (mTOR), the principal regulator of cellular homeostasis, underlies the biological effects of engineered nanoparticles, including regulation of cell death/survival and metabolic responses.

Growth hormone (GH) is a principal regulator of somatic growth in vertebrates, being produced in the pituitary gland and regulated by neuroendocrine controls integrating external environmental (e.g. increased daylength and temperature in the spring) and internal metabolic (e.g. energy status) signals.

The F.D.A.'s physical isolation belies its position as the nation's principal regulator of consumer products.

Aldosterone serves as the principal regulator of the salt and water balance of the body and thus is categorized as a mineralocorticoid.