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A principal problem of insurance risk theory is to find the probability of ultimate ruin.
That is why David Hilbert, who in 1928 challenged the mathematical community to solve the decision problem, called it "the principal problem of mathematical logic".
They decided to execute a "definitive depth-attitude survey", to explore the premise that the principal problem of advertising is not with the general public but with criticism of it that stems through though-leader groups.
However, the absence of the design variable is the principal problem of composite sandwich construction.
The government authorities across the globe and experts mention that the dumping of plastics waste and non-biodegradable is a principal problem of the dangerous environmental pollutions.
The exact documentation is a principal problem of quality assurance systems (QAS), from the very beginning of the design to the final implementation and continuous operation of the system.
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Some principal problems of the classical approach for parametrical identification are discussed.
He was admitted because of the principal problems of dehydration, syncope, and possible tickborne illness.
Microbial infections have become one of the principal problems of public health in the world, affecting all countries, developing or developed.
The effects of MPH on attention result from a combination of noradrenergic and dopaminergic mechanisms [ 12], which are assumed to ameliorate the two principal problems of attention deficiency and impulsivity/hyperactivity in children with ADHD.
However, it is useful to illustrate the principal problems of a 'general gating' mechanism: The barrier would break down whenever the gate is open, and because facilitated transport load is so high that NPCs must even transport many cargoes in parallel (Ribbeck and Görlich, 2001), such mechanism cannot explain how NPCs keep nuclear and cytoplasmic contents separated from each other.
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