Sentence examples for principal problem as from inspiring English sources

The comic characters Mr. De Niro has been playing in the last few years, like Louis and the smiler-with-a-knife political consultant of "Wag the Dog" (1997), represent, I think, an ingenious solution to his principal problem as an actor: how to use his enormous reserves of power without becoming predictably, formulaically "powerful".

Author's response: While preparing the paper we faced an obvious principal problem as proving a nonexistence of anything is usually difficult and to some extend dubious.

In this paper, it is our intention to lay the theoretical foundation which will enable us to fully investigate the second-order optimality and duality aspects of our following principal problem (P) as well as its semiinfinite counterpart in a series of papers.

The unaffordability of staying out the labour market for extended periods is cited as a principal problem by these women.

While moving in itself is a traumatic event as everyone knows, my principal problem is books.

Another principal problem was the difficulty in establishing a density value as threshold for lesion detection as a result of partial volume effects and motion artefacts.

These factors appear to function as main determinants of drug resistance, the principal problem for successful cancer chemotherapy.

A principal problem, however, is to obtain experimental data for each of these candidates, such as the full-length RNA sequence and its function.

I call that the "dumb principal" problem.

That's the other principal problem.

"The principal problem is our schools.