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Since this property is reminiscent of "unlocked nucleic acid" (UNA) which is widely used for siRNA technologies to minimize off-target effects,[ 23, 44] we have highlighted the principal potential of 2′-SCF3 RNAs for siRNA design as a promising novel application of this modification.
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In three cases, the principal potential hazard of the substitutes is acute eye, skin and/or respiratory irritation.
The principal potential impediments to ETR include: mistrust of the government, implausibility of the policy, means of hypothecation, information asymmetries, the political system, the structure of government, the macroeconomic environment, the impact on competitiveness, inequity between sectors, regressivity, elasticities and the level of the tax, terminology, and the marketing of ETR.
The principal (potential) novelty and scientific importance of the current study come from the demonstration of the role of Brahma in intestinal stem cell (ISC) regulation and of mechanisms by which its action is regulated.
Alkaloid metabolites were proved to be the principal potential biomarkers.
The rationale, history, principal issues, and potential of fuel cell-powered rail vehicles address a major application of hydrogen fuel cell power.
The rationale, history, principal issues, and potential of fuel-cell-powered rail vehicles address a major application of fuel-cell motive power.
Predictably, in this latest remix, political intrigue and racial grandstanding, combined with vicious attacks on the accusers, have obscured the principal inquiry: the leadership potential of a presidential candidate.
To investigate the potential of principal component regression for multi-line genomic prediction, an in-depth analysis of PC of the SNP genotypes will be presented.
The results show the potential of the principal components as damage indices for quantifying integrity conditions of concrete structures.
The potential of a principal component analysis of the molecular descriptor data to improve the TQSPR performance is assessed and a new stopping criterion for QSPR refinement based on the discrepancy principle is introduced.
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CEO of Professional Science Editing for Scientists @ prosciediting.com