Sentence examples for principal pathogenic factor from inspiring English sources

While there has been significant progress in the understanding of SLE genetics, which includes mapping of multiple SLE susceptibility loci/genes in the human and murine genome, to date no single or combination of structural gene defect has been identified as a principal pathogenic factor in inducing SLE [1], [2], [3].

We next wished to confirm these data in a second group of patients with the principal pathogenic factor being beta cell destruction.

Helicobacter pylori is the principal pathogenic factor in gastritis, peptic ulcer, and even gastric cancer and mucosa-associated lymphoid tumors [ 1, 2].

EBV was not the primary pathogenic factor in our samples.

ZnT8A are not primary pathogenic factors in type 1 diabetes.

The expression of HIF-1α was analyzed in the context of the hypoxia level (as evaluated by pimonidazole staining), which is an established pathogenic factor for DN and the principal regulator of HIF.

Hepcidin is the main regulator of iron metabolism and a pathogenic factor in iron disorders.

Autoimmunity has long been proposed as a possible pathogenic factor for HaNDL [4].

In this regard, increasing evidence shows that neuroinflammation is a pathogenic factor in drug-resistant epilepsies.

This should be valued as an additive pathogenic factor in diseases with disturbed energy metabolism.

Increased levels of reactive oxygen species (ROS) are a crucial pathogenic factor of osteoporosis.