Sentence examples for principal obstacles for from inspiring English sources

In turn, it is one of the principal obstacles for the United States in its effort to build a stronger alliance with a country to which it gives more than a billion dollars a year in aid.

Thus, genetic variability of HIV-1, especially of the envelope glycoprotein, remains the principal obstacles for elaborating an efficient vaccine against AIDS [9].

Principal obstacles for the clinical application remain the effects of immunosuppression, induced-carcinogenesis and teratoma formation observed in the experimental models [ 3, 4].

Due to the simplicity of fibre array generation, there is no principal obstacle for upscaling the method to large-scale production.

Tumor metastasis is the leading cause of breast cancer-related mortality and remains to be the principal obstacle for the successful chemotherapy of breast cancer.

The principal obstacle for assessing tropical cyclone hazard (and many others), for example, is the shortness of the historical/instrumental event record (over a few decades up to a couple hundred years).

Whereas several BBB-crossing bispecific antibodies have been developed using transferrin receptor antibodies as BBB carriers, the principal obstacle for capitalizing on the future promise of CNS-active antibodies remains the scarcity of known, characterized RMT receptors which could be exploited for the development of BBB carriers.

The merits of this view notwithstanding, the principal obstacle for directly testing this hypothesis in humans is the paucity of information about actual visual experiences.

In addition, we speculated that the complex composition of the spinal segment tissue, which contains different neuronal and glial cells and different cells in the supporting connective tissue, may be the principal obstacle for a correct tissue dissection and subsequent quantification of miRNA expression.

"A decade ago, many of the principal obstacles in the fight for stronger gun laws were in the leadership of the Democratic party," said Arkadi Gerney, a longtime gun control advocate and gun policy expert at the Center for American Progress.

Another of the principal obstacles to finalising the arrangements for the marriage was financial.