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The principal machineries maintaining proteostasis are the ubiquitin proteasomal and lysosomal autophagy systems, where heat shock proteins play a crucial role.
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To gain insights into the molecular mechanism of atRA-triggered HDAC3 nuclear enrichment, we monitored in vivo interaction of HDAC3 with exportin (the principal export machinery, CRM1) and importin-β1 (karyopherin β1) (Fig. 3B).
Principal imports include machinery and foods.
Panama's principal imports are machinery, fossil fuels, transportation equipment, and chemicals and chemical products.
Principal imports include machinery and equipment, vehicles and transport equipment, and chemicals.
Principal exports include machinery and equipment, timber, textiles, metal and metal products, and processed foodstuffs.
Principal exports include machinery, electronics, textiles, transportation equipment (notably, automobiles), and clothing and footwear.
Principal imports include machinery, motor vehicles, ships, iron and steel, chemicals and chemical products, and food products, especially fruits and vegetables.
In the Turkish sector citrus fruits, potatoes, carobs, and textiles are the principal exports; foodstuffs, machinery, and transportation equipment are the major imports.
Principal imports include food, machinery, road vehicles, and chemicals and chemical products.
These effects could be traced mechanistically to an inhibitory function of the porphyrin in the principal cellular protein degradation machinery: the proteasome.
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