Sentence examples for principal drawbacks are from inspiring English sources

However, the principal drawbacks are that electron-beam modification occurs under ultra-high vacuum conditions, limiting the potential of this technique for multicomponent biomolecule nanopatterning.

The chariot's principal drawbacks were its expense and unsuitability for difficult terrain.

The principal drawback was soprano Barbara Frittoli, her voice too small and her tone too shrill for comfort.

For me, the principal drawback is the growing gap between my age and that of the students, something well known to every teacher.

The principal drawback is that no inference to the underlying target population is possible.

The principal drawback is the lasting presence of the transposase, which could remobilize the transgene once it has been inserted.

These advantages include high selectivity and benign environmental impact; however, a principal drawback is low yield and/or productivity, which limits economic viability.

A brief description of some new NMR screening techniques applied to drug discovery is given in this review, and their principal advantages and drawbacks are discussed.

Operational drawbacks are being reduced.

The principal drawback, however, is Wolfgang Koch's curiously bland Sachs.

The principal drawbacks of LSTOK are the difficulties involved in its implementation.