Sentence examples for principal difficulty to from inspiring English sources

The importance of liquid helium temperature cooling technology in the aerospace field is discussed, and the results indicate that improving the efficiency of liquid helium cooling technologies, especially the liquid helium high frequency pulse tube cryocoolers, is the principal difficulty to be solved.

These mutation mechanisms confer an unpredictable, evolving character to the influenza viruses, which is the principal difficulty to overcome when designing a vaccine.

A principal difficulty is to obtain an efficient pentose uptake in the presence of high glucose and inhibitor concentrations.

The principal difficulty at present is that there are no official rules.

I had not dreamed up the idea that my principal difficulty with Murdoch was my refusal to turn the paper into an organ of Thatcherism.

The principal difficulty associated with this technique is to correct for the parallel conduction through the electrolyte.

An additional quantitative insight into the potential impact of this unobservable variation on the correlation structure of microarray data is possible as described in Section 4. Recalling the model given by (1), we give a formula that allows us to better understand the principal difficulty brought about by the random nature of the parameter ν.

The principal difficulties were linked to the obtaining of bottles and caps for the ABHR bottling.

The principal difficulty with the matchlock mechanism was the need to keep a length of match constantly smoldering.

The principal difficulty has been the assembling of material on which to base such studies.

My principal difficulty, though, was the casting of Stephen Fry as the meant-to-be endearingly eccentric art professor and museum curator.