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In fibrotic livers, aHSCs were the principal cells that bound the carrier.
Thus, in the BLA, GABAergic interneurons are more vulnerable to seizure-induced damage than principal cells.
Both direct and indirect approaches model the excitatory synaptic interaction between neighbor principal cells, usually named collateral excitation.
The EEG/MEG signal is generated primarily by the summation of the post-synaptic potentials of cortical principal cells.
CA1 was modeled as firing of principal cells which are stimulated by the bursting of thalamic neurons and inhibited by local inhibition.
The megamap model is designed for a network of principal cells in the CA3 subregion of the hippocampus, a region crucial for learning and memory [20 22].
Inhibitory cells receive convergent excitatory inputs from afferent pathways, as well as local collaterals of principal cells, and provide feedforward or feedback inhibition within the circuitry.
Using design-based stereology combined with glutamic acid decarboxylase (GAD) 67 immunohistochemistry, we found a more extensive loss of GABAergic interneurons compared to the loss of principal cells.
Crucially, these changes spoke to an increase in the sensitivity of principal cells to intrinsic inhibitory afferents and a transient loss of excitatory inhibitory balance.
The appearance of MTA1 protein in the principal cells from day 35 coincides with the complete differentiation of principal cells from columnar cells and their further differentiation to principal cells and apical cells.
Indeed, we found that DTK signaling regulates levels of DILP5 in principal cells under nutritional stress.
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