Sentence examples for principal cell surface from inspiring English sources

CD44 is a facultative cell surface proteoglycan expressed as several isoforms [1], and the principal cell surface receptor of hyaluronate [3], [4] (HA), the major component of the extracellular matrix [5].

Human and murine cells are most efficiently infected by HSV-2 upon interaction of gD with one of two principal cell surface receptors, herpes virus entry mediator (HVEM) or nectin-1 [1].

CD44 is a polymorphic proteoglycan and functions as the principal cell-surface receptor for hyaluronate (HA).

4-Methylumbelliferone had no significant impact on mRNA expression of CD44, a principal cell-surface receptor of HA.

Principal component analysis (PCA) plot of cell surface profiles (Fig. 3A) revealed a relationship between HMEC of different donors stimulated to grow in the presence of endothelial cell growth supplement (ECGS) or tumor-conditioned medium (cancer cells were cultured to generate the conditioned medium).

We identified β1 and β3 integrins as the principal binding partners for tTG on the cell surface, and showed a major role of the integrin-tTG complexes in cell-ECM interactions and outside-in signaling [20], [21], [55].

Following binding of hepcidin to the principal iron exporter FPN-1 at the cell surface, this latter is internalized and subsequently lysosomally degraded [ 117].

To date, these cluster designation (CD) cell surface molecules are the principal markers used to qualify these tumorigenic cells as cancer stem cells, and the fact these cells can apparently undergo differentiation to produce other types.

For the first time, we characterize the cell surface glycan structures of principal allergic effector cells, which by interaction with glycan-binding proteins (e.g. lectins) have the possibility to dictate cellular functions, and might thus have important implications for the pathogenesis of inflammatory and allergic diseases.

HA is one of the principal ECM molecules and together with its CD44 cell surface receptor, it is implicated in cancer cell invasion and metastasis [ 62].

In principal, the most attractive features for this purpose are cell surface proteins that are uniquely represented or particularly highly expressed in the metastasis-prone cells.