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The principal bottleneck for practical application of monolith reactors is the synthesis rather than the design of the catalytic monolith.
The principal bottleneck for the utilization of small-molecule probes in live cells is the shortage of methodologies for targeting them with very high specificity to biological molecules or compartments of interest.
As memory access is a principal bottleneck in current-day computer architectures, a key enabler for high performance is masking the memory overhead.
Technological innovations are penetrating all areas of science, making predominantly human activities a principal bottleneck in scientific progress while also making scientific advancement more subject to error and harder to reproduce.
► In a Policy Forum in this week's Science, four scientists argue that "predominantly human activities" are "a principal bottleneck in scientific progress" and propose that "a new generation of artificial intelligence (AI) systems can radically transform the practice of scientific discovery.
Currently, the principal bottleneck for the progress of pathway analysis of metagenomics data remains assignment of function and assembly of operons and metagenomes.
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The developed approach thus overcomes the principal large-scale problem bottleneck of the original Kansa method.
The resulting bottleneck is the principal reason that many of today?s Ph.D.s are consciously turning to postdoc appointments--not because they desire a higher level of training, but mainly as a form of temporary employment (not necessarily underpaid) while waiting for other career options.
In its recent study of AI for the public good, McKinsey cites access as one of the principal barriers: of the 18 bottlenecks identified by McKinsey, six relate to data availability, volume, quality, and usability.
Our results reveal key connections between canonical correlation analysis (CCA), principal component analysis (PCA), the Gaussian information bottleneck, Wyner's common information, and the Ky Fan (nuclear) norms.
After the training, the values of the bottleneck correspond to the nonlinear principal components of the given dataset.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com