First, we relied on clinical not pathological diagnosis, and this might in principal affect the specificity of the results.
We find no evidence for the linker polypeptide engaging lipid modifying enzymes (PIP5KIγ [ Figure 9B], PLD, DGKδ1 [not shown]) that could, in principal, affect clathrin coat assembly without physically being enriched at coat assembly zones.
Mr. Ruckleshaus said that the principal crops affected by DDT cancellation, if sustained, would be cotton, citrus fruits and certain vegetables.
The two principal additions affected only the south wing, enlarging it until it formed a solid rectangular structure 70.80 by 72.60 meters in plan.
The principal nations affected were the Sauk, Foxes, Chippewa, Ottawa, Potawatomi, Winnebago, Sioux, Menominee and other northern Indians.
Miyagi prefecture - the principal zone affected by the tsunami - has a population of 2.3 million, while Fukushima prefecture - where the bulk of the nuclear exclusion zone is currently located - contains 2 million inhabitants.
The liver is the principal organ affected, as it is the first organ encountered after absorption by the gastrointestinal tract, though other organs, especially the kidneys, are susceptible to the toxins.
The liver is the principal organ affected, as it is the organ which is first encountered after absorption in the gastrointestinal tract, though other organs, especially the kidneys, are susceptible.
In both cases the principal category affected is "cancer" (Table 1).
The principal countries affected include Australia, South Africa and Zimbabwe.
