Sentence examples for primordial virus from inspiring English sources

Are viruses as a whole monophyletic, i.e., ultimately descend from a single primordial virus or polyphyletic, i.e., have multiple origins?

Forterre propounds a different scenario of evolution that includes a primordial virus world as well but considers eukaryotes to be one of the primary lines of descent in the evolution of cells [ 35, 45- 47].

Clearly, under the « primordial eukaryotic lineage » scenario, viral hallmark genes in the NCLDV could plausibly originate from the primordial virus world, and transfer of genes from these viruses to the eukaryotic hosts potentially could be a major route of evolution.

Here, in order to be concrete, we attempt a reconstruction of the earliest events in the evolution of primordial virus-like entities within the framework of this model although our general conclusions do not seem to hinge on any particular model of organization of the ancient, precellular life.

These observations are consistent with an immunologic arms race between a primordial herpes virus and an inserted copy of the virus in which the virus would exhibit conservation of "high information content" structural domains with rapid divergence of primary sequence similarity.

Novel to this work is the suggestion that the DDE recombinase responsible for the origins of acquired immunity was encoded by a primordial herpes virus, rather than a "RAG transposon".

The remainder of this work will elaborate a novel hypothesis, namely that a primordial herpes virus, rather than a transib or similar DNA transposon was the source of the primordial RAG-1 protein, and that understanding the biology of herpes virus replication is therefore essential to understanding the origins of the acquired immune system.

These domains are present in a remarkably diverse array of cellular hosts, ranging from small microbes to complex vertebrates, providing further support to the ancient and primordial nature of viruses [ 16] and highlighting their crucial contribution to the biosphere [ 47].

At any rate, Forterre's proposal on the primordial role of viruses in Domain genesis could concur with the hypothesis of a phagocytic RNA-LUCA but without adopting the idea of a nuclear origin by phagocytosis.

The idea of a primordial origin of virus-like entities, of course, is old, even if unpopular lately (at least prior to the work of the Bamford group on the JRC structure in diverse viruses and the discovery of the mimivirus – all this is cited here).

Traditionally, these ideas have revolved around three themes: i) origin of viruses from primordial genetic elements, ii) degeneration of unicellular organisms to the virus state, and iii) "escaped genes" hypotheses deriving viruses from genes of cellular organisms that have switched to the selfish mode of reproduction (reviewed in [ 40- 45]) (Table 4).