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3. The conservation of the hallmark genes between prokaryotic and eukaryotic viruses seems to be another telltale sign of primordial origin of these genes.
The idea of a primordial origin of virus-like entities, of course, is old, even if unpopular lately (at least prior to the work of the Bamford group on the JRC structure in diverse viruses and the discovery of the mimivirus – all this is cited here).
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The pZBD of GluRS, present at the N-terminal catalytic domain, is of primordial origin.
Consistent with their primordial origin, Fe-S clusters can readily assemble onto their protein targets without any help in the presence of iron and sulfide.
Amaterasu (Okami, 2006) Sun goddess, primordial mother and origin of all that is good, Amaterasu (or Ammy to her friends) is an unforgettable protagonist.
The primordial hairpin duplication origin of tRNAs is a large and fairly complicated body of literature and I did not evaluate it exhaustively.
It may also have implications for prebiotic evolution of genetic machinery at the primordial stages of the origin of life.
Since the pivotal experiment by Orò [ 9] on the synthesis of adenine from HCN, numerous studies were devoted to assess the role of this compound in the origin of primordial nucleic acids [ 10].
A few authors [ 19, 416, 417] have stressed the potential importance of high radioactivity on primordial Earth for the origin of life, albeit without suggesting how the energy of ionizing radiation could be used for biochemically relevant syntheses.
It has been postulated that HT is a very important mechanism, the source for much biological innovation; indeed, some of the most significant events in cell evolution have been associated with HT, such as the origin of the primordial eukaryote cell, and HT has contributed to the characteristics of the multicellularity [ 28].
Some hypotheses attach significance to inorganic compartments in evolution of primordial chemistry and biochemistry for the origin of life.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com