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Hence the 59 residue repeat likely derives from gene duplication of a primordial module sequence.
Our model leads to some significant conclusions on the role of introns in hop gene evolution: i) Phase-0 introns were critical for serial exon shuffling recombinations of a primordial module [ 28, 47– 49] composed of symmetric exons « miniexon – phase-0 intron – TPR domain − phase-0 intron − Ch.
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We downloaded WGBS data of mouse primordial germ cells to demonstrate TXN module of MethGo [ 23].
Most modules were significantly co-expressed within developmental processes such as leaf primordial and budset, while only a few modules were co-expressed in stress responses such as biotic infection and elevated [CO2].
The systems biology approach taken with this network analysis of primordial follicle development identified clusters and modules of genes involved in this critical development process.
The mammary primordial epithelial and mesenchymal core network modules were interconnected to identify prospective mediators of mesenchymal-epithelial interactions (Additional file 9).
This activity may represent a relic of editing exhibited by a primordial aaRS consisting solely of the catalytic module.
It will help us to trace how the primordial promiscuous enzymes were assembled progressively in functional modules, as the present pathways diverged from ancestral pathways to give birth to the present-day mechanistically diversified superfamilies.
A gene bionetwork analysis identified gene modules of coordinately expressed interconnected genes and it was found that different gene modules appear to accomplish distinct tasks during primordial follicle assembly.
A similar systems biology approach has been used previously to identify coordinately and interconnected expressed gene modules and gene networks that regulate the primordial to primary follicle transition which is the subsequent stage of ovarian follicle development [ 31].
The second example module exhibits high expression similarity in the leaf primordial experiment (average pair-wise correlation of 0.96) and annotations indicate a role in photosynthesis.
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