Sentence examples for primordial function of from inspiring English sources

Particularly, the cell biology and pathobiochemistry of intestinal disaccharidases has occupied a major part of this workshop by virtue of the primordial function of the sucrase-isomaltase enzyme complex in carbohydrate and human starch digestion to glucose (α-glucogenesis) [1].

In this regard, it is notable that ribosomal biogenesis has been proposed to be a primordial function of Myc during evolution [5].

Nvp63's protein structure, its localization in early gametes, and function suggest that the induction of apoptosis in the germ line upon genotoxic stress is a primordial function of the p53 family that existed already before bilaterians evolved.

Evolutionary conservation analysis of these binding sites is greater when adjacent to up-regulated genes than down-regulated genes, suggesting the primordial function of PPARγ/RXR is in the induction of genes.

When coupled with the observation that the evolutionary conservation of PPARγ/RXR binding sites is greater when adjacent to upregulated genes than downregulated genes suggest that the primordial function of PPARγ/RXR is the induction of genes involved in lipid and fatty acid metabolism.

For example, there are several lines of evidence to suggest that the RAG1 and RAG2 genes involved in V(D J recombination originated from a hAT DNA transposon that was domesticated to fulfill this primordial function of the adaptive immune system [19], [20].

The observation that the majority of Myc-activated genes controls ribosome biogenesis and translation indicates that these are the main and presumably primordial functions of Myc proteins.

With only one p53 family member expressed as two detectable isoforms, Drosophila is a genetically tractable model to explore the "primordial" functions of p53 in addition to its well-known functions in mediating apoptosis in the presence of genotoxic stress.

Such findings suggest that muscle miRNAs examined have been under strong selective constraint throughout the evolution of vertebrates, thereby reflecting an acquirement of primordial functions on muscle biology.

These and other observations suggest that tumor suppressive roles for the p53 family were co-opted from primordial functions, some of which may have been linked to meiotic recombination (Lu et al., 2010).

A number of recent studies have focused on the complexity of the urancestor, its primordial functions, alternative rootings of the tree of life, and the rampancy of HGT [ 6- 123 23, 46].