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A comparison of the increased time spent in the morphine-paired chamber during the morphine-prime test session (morphine place preference on prime session minus baseline place preference from previous test session) was significantly different between post-dependent and non-dependent rats (t41=2.77; p=0.0085; Figure 2a).
A comparison of the change in locomotor activity during the morphine-prime test session (locomotion on prime session minus baseline locomotion from previous test session) showed significant differences between the non-dependent and post-dependent groups (t41=2.39; p=0.022; Figure 2b).
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(b) Locomotor activity (numbers of beam breaks) was depressed in non-dependent rats during the morphine-prime session as compared with the previous test session, but not in post-dependent rats.
In the multiple shocking protocol, rats went through a foot shock priming session before each drug test.
Means (±SEMs) for difference scores following the morphine-prime (morphine-prime test session minus the previous test session) are shown for morphine- and placebo-pelleted animals during 15-min CPP tests.
During protracted abstinence, the locomotor response to acute morphine was also changed during the prime test session (Figure 2b).
Non-dependent rats showed significantly decreased locomotor activity (number of beam breaks) during the morphine-prime test session as compared with the previous session, whereas post-dependent rats did not.
If Tropical Storm Hanna interrupts the United States Open on Saturday, the U.S.T.A. said it would move the men's semifinals to Sunday afternoon and the women's final to the prime-time session Sunday.
Results showed that non-dependent rats (previously placebo-pelleted; n=22) had enhanced morphine place preference during the morphine-prime test session as compared with their previous test, whereas post-dependent rats (previously morphine-pelleted; n=21) did not.
The celebratory hand slap had become a tad old in our book, but Johan Berg and Aleksander Aurdal give the gesture an acrobatic makeover at Prime Park Sessions on the Stubai Glacier in Austria.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com