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Ad-H4, rH4, the hetrologous prime boost combination, non-vaccinated, and BCG vaccinated mice were included.
The trial vaccination regimen was a candidate prime boost malaria vaccination.
We used two different prime boost regimens for aged mice.
This supports the prime boost strategies being employed for some new TB vaccines currently under development.
The authors would like to thanks all members of the European Prime Boost Consortium, contract number QLK3-CT-2002-02010.
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However, the classical prime-boost approach requires lengthy time periods between priming and boosting.
The ultimate T cell responses in prime-boost regimen tend to be determined mainly by the priming efficacy.
These results have boosted expectations for the prime-boost vaccinations.
The F protein-specific prime-boost strategy induced partial protection.
All vaccine candidates were evaluated in a mouse model in prime only or prime-boost regimens.
The humoral and cell-mediated immune responses following prime-boost vaccination were assessed.
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