However, others have shown that the T cell priming ability of aged BMDCs was equivalent to their younger counterparts [ 6].
The studies reviewed here have primarily focused on BCR regulation; however, the chief responsibility of MZ and B-1 B cells is their primed ability to sense, engage, and combat innate agonists.
MUTZ3-DC display the full range of functional MHC- and CD1d-mediated antigen processing and presentation pathways and upon maturation (induced by cocktails comprising IL-6, PGE2, TNF-α, IL-1β, IFN-α, or Poly:IC) up-regulate co-stimulatory molecules, express CD83, and display an enhanced allogeneic T-cell priming ability in mixed leukocyte reactions (MLR) [ 34, 40].
We proved that the IFNβ+ cells exhibited the hallmark characteristics of Tip-DCs as they produced iNOS and TNF and possessed T cell priming abilities.
Seeing him in his prime, the ability to dominate a stage Gil at his best was an all-timer".
Seeing him in his prime, the ability to dominate a stage — Gil at his best was an all-timer".
The KOLL gives users of Amazon's e-readers who also shell out for its one-year membership, Prime, the ability to borrow from a catalogue of Kindle e-books for free.
They have a small window of prime earning ability".
DOI: http://dx.doi.org/10.7554/eLife.03641.017 Finally, we examined PRIME's ability to build personalized models of cancer patients and predict their prognosis based on gene expression levels collected from biopsy samples.
Here we introduced a possible way to overcome this hurdle, as demonstrated by PRIME's ability to utilize clinical data and build cell-specific GSMMs tailored for each individual patient.
