Sentence examples for primary tumor model from inspiring English sources

Although CD206 prevalence was highly heterogeneous, we found that scVEGF/177Lu induced a decrease in average CD206 prevalence in tumor tissue in MDA231luc primary tumor model.

In orthotopic primary tumor model, a combination of Doxil and scVEGF/177Lu was more efficient in tumor growth inhibition than each treatment alone.

First, the primary tumor model system examined miR-16 deletion.

This approach, however, mimics only the final stages of bone colonization by extravasated cancer cells and replicates a primary tumor model rather than a metastasis model.

Researchers have established a variety of GFP-labled primary tumor model for FMI and carried out in vivo screening and evaluation for antitumor growth and antiangiogenesis drugs.

The discordant results reported here between the effects of miR-16 overexpression in an orthotopic transplant model in immunocompromised mice and miR-16 deletion in a primary tumor model in immunocompetent mice demonstrate the importance of utilizing complementary gain-of-function and loss-of-function approaches and primary tumor model systems for the study of metastasis.

For the primary tumor growth model, BALB/c-nude female mice were orthotopically injected with 1 × 106 LM2 cells into the mammary fat pad.

To elucidate the effect on lung metastasis in clinical status more clearly, we next prepared a primary tumor resection model (Fig.  5a).

We prepared a primary tumor resection model, in which pulmonary metastasis was not obvious at the time of primary tumor resection but became apparent at 3 weeks after resection.

In order to generate a primary tumor resection model of OS, LM8 cells (1 × 10 cells/200 μl of PBS) were injected into the subcutaneous tissue of the backs of syngeneic C3H mice.

As osteosarcoma xenografts and cell lines still express histological subtype-specific mRNAs that are characteristic of the primary tumor, these model systems are representative for the primary tumor from which they are derived, and will be useful tools for studying mRNA expression and pathways important in high-grade osteosarcoma.