Melanin antigens have also been shown to induce uveitis wherein CD4+ T helper cells are mediators of inflammation, and the primary target tissue is the uvea.
Majority of the researcher worldwide have used genetic engineering to tailor wheat for specific end-use by using immature embryos as the primary target tissue for the delivery of desired foreign genes.
The primary target tissue of ADLD is the CNS, specifically myelin.
In RA, TNFα is overexpressed in the primary target tissue of the disease - the synovial membrane [ 50].
The primary target tissue of OA is the articular cartilage, a physiologically nonself-renewing, avascular tissue that functions as the load-bearing joint surface.
Pathological changes were not found in any other tissue, including sciatic nerve and spinal cord, suggesting that skeletal muscle is the primary target tissue of this disease.
The epithelial lining of respiratory air passageways is a primary target tissue for toxicity and carcinogenesis in man and in animal models of human disease.
Although 1-NN causes both centrilobular liver damage and bronchiolar epithelial damage in rats, the lung is the primary target tissue.
Third, methylomic analysis was performed on DNA from buccal cells, which may not represent the primary target tissue involved in asthma.
