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Melanin antigens have also been shown to induce uveitis wherein CD4+ T helper cells are mediators of inflammation, and the primary target tissue is the uvea.
Majority of the researcher worldwide have used genetic engineering to tailor wheat for specific end-use by using immature embryos as the primary target tissue for the delivery of desired foreign genes.
The primary target tissue of ADLD is the CNS, specifically myelin.
In RA, TNFα is overexpressed in the primary target tissue of the disease - the synovial membrane [ 50].
The primary target tissue of OA is the articular cartilage, a physiologically nonself-renewing, avascular tissue that functions as the load-bearing joint surface.
The epithelial lining of respiratory air passageways is a primary target tissue for toxicity and carcinogenesis in man and in animal models of human disease.
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This concept urged translational researchers to reassess the cellular source of IL-17 in the primary target tissues of a various diseases.
For BoNT-A and VEE, the primary target tissues are inaccessible, although VEE has been shown to interact with lymphoid cells [ 21].
Changes in calcium influx in primary insulin target tissues may contribute to peripheral insulin resistance.
Microbiota has effects beyond local tissue, with adipose tissue considered a primary target.
The primary target of ionizing radiation in tissue is DNA and the biological responses to the DNA damage signal are complex.
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