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The sampling protocol also produces an ordered list of alternative sites close to the primary target site, should the primary target site prove inaccessible.
The mucosa represents the primary target site and thus the first barrier for most microbial pathogens.
The further in vitro inhibition activity against acetohydroxyacid synthase (AHAS) enzyme and molecular docking indicated that AHAS might be the primary target site for these newly synthesized compounds.
The concentrations of the primary target site primers in the multiplex PCR are shown in Supp.
CHIKV probably does not share this tropism (33 ), although the primary target site of CHIKV infection is unclear.
Early radiation enteropathy occurs in the actively proliferating intestinal crypt cell compartment of intestinal mucosa, which is the primary target site of radiation injury.
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The primary target sites of cigarette smoking are the lungs and heart.
However, cotton fibers are unlikely to be primary target sites of attack by fungi.
Overall, the data can be explained by supposing that the primary target sites underlying general anesthesia are amphiphilic pockets of circumscribed dimensions on particularly sensitive proteins in the central nervous system.
The indicator of primary target is the site of point mutations that confer quinolone resistance.
Primary mutations in target site genes generate resistance to the quinolone antimicrobial nalidixic acid, making it useful as a surrogate marker of decreased susceptibility to fluoroquinolones [ 12], as resistance to nalidixic acid correlates with decreased susceptibility to ciprofloxacin and hence to potential treatment failure [ 1315]5].
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