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E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance.
Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells.
Seki, A. & Rutz, S. Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells.
Su, S. et al. CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients.
Finally, we find an enrichment of associated variants to markers of open chromatin in CD8+ memory primary T cells.
However, a relatively small increase in IL-27-induced BST-2 was observed in the Jurkat T cell line (Fig. 1D) compared to primary T cells (Fig. 1B).
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Primary T-cell immunodeficiencies -- 36.
In primary T-cells, expression levels of Foxo1 protein is already high, and Foxo13A-NPs only led to modest increases.
S.P. and F.P. performed and supervised experiments related to NOTCH activation into primary T-ALL samples and provided crucial materials.
Furthermore, purified mucin did not produce a mucin-specific response in mucinous pancreatic tumour patients' primary T-cells even in the presence of antigen-presenting cells.
Non-enzymatic activities of heparanase include enhanced adhesion of tumor-derived cells and primary T-cells.
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