Sentence examples for primary susceptibility from inspiring English sources

Most guidelines recommend to first screen isolates for decreased susceptibility to extended-spectrum cephalosporins in primary susceptibility testing, and then to carry out a confirmatory test to verify ESBL production (Gazin et al. 2012; Garrec et al. 2011; Rupp and Fey 2003).

The three primary susceptibility genes for CP include the cationic trypsinogen gene (PRSS1) [10], the cystic fibrosis transmembrane conductance regulator gene (CFTR) [11], [12], and the pancreatic secretory trypsin inhibitor gene, also known as serine protease inhibitor Kazal type 1 (SPINK1) [14], [15], [15].

The authors suggest that variation in the CPR gene may be a primary susceptibility determinant in paraquat toxicity.

The findings imply that loci increase the risk of both PD and AD and that the pathological overlap could instead be "downstream" of the primary susceptibility genes that increase the risk of each disease [ 6].

23 26 27 Although SAMP1/Yit mesenteric lymph node CD4+ T cells are capable of adoptively transferring ileitis to severe combined immunodeficient (SCID) mice, increased IEC paracellular permeability appears to be the primary susceptibility factor in this model.

Since our results implicate downregulation of DAPK1 not only as the primary susceptibility factor in a large family, but also as a major event in sporadic CLL, it is quite possible that trans-acting factors, such as RNA genes (Calin and Croce, 2006, Esquela-Kerscher and Slack, 2006), play roles in the deregulation of DAPK1, and other genes, in CLL.

The power of genetic data lies in their ability to highlight primary susceptibilities to disease, that is, they illuminate aetiology.

Cumulative data demonstrate that the primary susceptibilities are to Mycobacterium tuberculosis, (presumed) bacterial sino-pulmonary infections, Histo-plasma candulatum and JC virus (all associated with TNFα-inhibitors) [ 72, 73].

The most significantly MS-associated SNP in the discovery dataset was rs3135391, a Class II SNP known to tag the HLA-DRB1*15:01 allele, the primary MS susceptibility allele in the MHC (O.R. = 3.04, p<1×10−78).

Finally, standard TB treatment should start with a four-drug regimen and primary drug susceptibility testing should be preformed systematically to optimize treatment, stop further transmission, and above- all, prevent the emergence of drug resistances.

The present study suggests that primary non-susceptibility to amphotericin B and fluconazole is common.