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Food is one of the primary substrates of the reward system in higher living organisms.
The primary substrates of MMPs are generally thought to be the ECM components.
The second-order rate constant for PAP was determined to be over 3 orders of magnitude greater than those determined for myo-inositol 1-phosphate (IMP) and fructose 1,6-bisphosphate (FBP), previously considered to be the primary substrates of this enzyme.
Our studies provide direct experimental evidence for the existence of flexible α-glucan chains protruding from solvent-exposed surfaces of starch granules and that these chains, which increase in number during hydrothermal processing, are the primary substrates of pancreatic α-amylase.
HLMVEC lysates incubated with LPS in presence or absence of different concentrations of ropivacaine were analyzed by Western blot, focusing on phosphorylated Cav-1 (pTyr-Cav-1), one of the primary substrates of Src, as well as the total amount of Cav-1 and β-actin.
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The primary substrate of laccases is lignin, an amorphous, complex cross-linked polymer consisting of phenylpropane units (Claus 2004; Moilanen et al. 2011).
Crystal structure of the FTO protein recently confirmed this, and indicated that single-stranded RNA is the primary substrate of FTO [16].
Previously, we reported that ICV infusion of 1 mg/kg hASM was the lowest effective dose to reduce lysosomal accumulation of sphingomylein (the primary substrate of hASM) in a mouse model of Niemann Pick A disease [16].
Deciduous leaves, the primary substrate of aquatic hyphomycetes, are highly seasonal in abundance in temperate climates [12] [14], with leaves most abundant in late autumn and winter and least abundant in summer and early fall [15].
Since Trx is a primary substrate of TR1 and since other Sec-deficient TR1 have demonstrated oxidative stress, we measured the Trx redox status to determine if the Sec-deficient C-terminal mutant TR1 altered the redox status of Trx.
Hazlett et al. [30] and Desrosiers et al. [31] revealed that TpTroA has high binding affinity for both Zn2+ and Mn2+, but Zn2+ is considered to be the primary substrate of TpTroA [32].
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