Suggestions(1)
Exact(5)
The study design, recruitment, baseline characteristics and primary study findings of the Partners in Prevention HSV/HIV Transmission Study are detailed elsewhere [14] [16].
Heterogeneity among primary study findings was explored using meta-regression analyses that examined a series of possible effect modifiers.
The interpretation of the primary study findings, and consequently a different thematic framework, may have emerged if an additional reviewer had undertaken analysis at this stage.
However, models not adjusting for chronic conditions, which are most likely to be plagued by endogeneity, did not alter the primary study findings.
The same analysis (ANCOVA) was run using the predicted EQ-5D and results compared to the primary study findings; Patients who received palliative chemotherapy had significantly better HRQoL at 16 weeks than those that did not (ANCOVA p = ·005).
Similar(55)
The primary study finding is that slum residents had a greater odds of having a facility delivery after the OBA programme was launched.
The primary study finding was that GPs and psychiatrists give very similar responses when asked about which depressive symptoms and broader outcome dimensions are most important in defining cure from depression.
A qualitative approach was chosen, since primary studies report findings for numerous heterogeneous outcomes and employ different data sets and statistical methods.
How can we best judge conceptual richness of primary qualitative study findings?
Future users of clinical trial data who identify findings that they consider to have clinical relevance should inform the primary study investigator of these findings, but must understand that all decisions related to notifying research participants of incidental or research genetic results reside with the primary study investigators and their IRBs.
In the light of the study findings, primary care physicians should seek for an effective management of these PPS, and closely monitor the patients' improvement, so in this way the chances of functional recovery would be increased.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com