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Thermally denatured proteins are a primary stimulus of the heat shock response [ 39].
Because the uterine environment is hypoxic it is thereby obvious that hypoxia may be the primary stimulus of vessel formation [ 3, 4].
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A primary stimulus for release of ATP from RBCs is the offloading of oxygen from the haemoglobin molecule [ 1, 3, 41- 43].
The primary stimulus for production of estrogen and other ovarian steroid hormones is the release of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), from the anterior pituitary.
Parenthetically, the extraction of physical information from atomically resolved imaging data, along with 3D imaging, provides the primary stimulus for development of progressive high-resolution STEM platforms [1].
In Mexico, the primary stimulus for development of antibody to Stx1 may be becoming infected with O55 or O111 EHEC rather than with O157 EHEC.
Because previous studies showed that high intraluminal pressure is the primary stimulus for upregulation of vascular MMPs (Lehoux et al., 2004), we compared pressure-induced MMP activation in cerebral arteries isolated from young and aged mice using the MMPsense 645 FAST substrate.
While this alone does not confirm that the RBC is the source of the ATP, nor that ATP is involved in the regulation of blood flow, it is a critical test of the hypothesis considering offloading of oxygen from haemoglobin is a primary stimulus for the release of ATP from RBCs.
The oral detection and analysis of exogenous substances is proposed to be the primary stimulus for the mechanism of drug tolerance.
Continued signal transduction through the VEGF/VEGFR-2 pathway is a primary stimulus for initiation and maintenance of tumour angiogenesis (Ellis, 2004).
Accordingly, engagement of the extracellular domains of epithelial CEACAMs serves as the primary stimulus for CEACAM-mediated transmembrane signaling.
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CEO of Professional Science Editing for Scientists @ prosciediting.com