Sentence examples for primary signalling pathway from inspiring English sources

Interestingly, the primary signalling pathway upregulated in muscle was the PI3K AKT pathway, a central control point for insulin-stimulated glucose uptake.

The primary signalling pathway involved in pro-inflammatory responses to a genetically related species, S. pneumonia, (> 99% homology by 16S rRNA to S. oralis, (Johnston et al., 2010)), involves TLR2 activation (Dessing et al., 2008; Beisswenger et al., 2009).

The major goal for the future is to elucidate the primary signalling pathways responsible for the diverse effects of pemphigus IgG such as inhibition of desmoglein binding, depletion of desmosomal components, loss of desmosomes, reorganization of the cytoskeleton and finally the induction of acantholysis.

daf-2 encodes a C. elegans IGFR homolog whose primary signaling pathway modulates the activity of the FOXO transcription factor DAF-16.

Remarkably, this wealth of developmental effects is all mediated through the same primary signaling pathway [ 5].

If ethylene responses all rely upon the same primary signaling pathway, how is it that ethylene can mediate so many different developmental responses?

The prototypical primary signaling pathway of M2 and M3 muscarinic receptors is inhibition of adenylyl cyclase and stimulation of phospholipase C PLCC), respectively, the latter leading to formation of inositol phosphates and diacylglycerol, which in turn mobilize Ca2+ from intracellular stores and activate protein kinase C (PKC), respectively [ 96].

Because canonical Wnt activation is associated with increased aldosterone production, whereas DACH1 and TGF-β do the reverse, we reason that TGF-β is likely to be the primary signaling pathway for DACH1, with Wnt activation being a secondary or compensatory response.

One of the primary signaling pathways activated by Gs-alpha is the cAMP pathway.

KEGG disease pathways were excluded to focus the analysis on primary signaling pathways.

Two-component systems are the primary signaling pathways that bacteria utilize to respond to their environment.