This qualitative study explores the barriers to primary care responsiveness to poverty as a health issue in a well-resourced jurisdiction with near-universal health care insurance coverage.
The aim of this study is to explore expert informants' perspectives on the barriers to primary care responsiveness to poverty as a health issue.
16 Patients exhibiting primary non-responsiveness to TNF inhibitors are likely to have non-TNF-α-mediated disease and consequently would be predicted to respond better to subsequent therapy with an alternative mode of action.
The inclusion of stakeholders on a more formal basis for example in a standing committee or by officially delegating health policy and implementation responsibilities to them can strengthen the effectiveness and responsiveness of primary care policies.
Using phosphoHistone H3 (pHH3) as a biomarker of barasertib-hQPA responsiveness in primary AML blasts we determined that Pgp and BCRP positive primary samples were less sensitive to barasertib-hQPA induced pHH3 inhibition (p = <0.001) than samples without these transporters.
In addition, the responsiveness of primary tumor cells may change over time as a malignancy progresses and could be affected by several additional clinical problems that emerge in patients, such as infections or organ failure.
These results indicate that the responsiveness to primary (inosine) and secondary (alanine) germinants is not compromised in Δger Qspores, and that these spores germinate normally in the presence of both germinants.
These results suggested a key role of hypoxia as a modulator of Wnt responsiveness in primary GBM cells.
Measures that have demonstrated good responsiveness in primary hip arthroplasty do not necessarily perform similarly in revision arthroplasty.
Christina Zechel (University Hospital of Schleswig-Holstein) focused in her talk on the responsiveness of primary cultures of stem cell-like brain tumor cells to mitogens.
While there are several molecules that Lifr may interact with [ 41- 43], Lifr expression is a primary determinant of cellular responsiveness to leukemia inhibitory factor (Lif) [ 44].
