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Organismal lifespan has been the primary readout in aging research.
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Although this response could be secondary to excessive tissue damage or necrosis, it is a further factor potentially compromising experimental interpretation, as inflammatory response and cell death constitute primary readouts in cardiac regeneration research.
The primary readout was change in critical temperature thresholds (CTT).
GFP-LC3 was used as a primary readout for autolysosome formation in live cells, as previously described by Shvets et al. [ 26].
GFP-LC3 was used as a primary readout, since either upregulation or downregulation in autophagic activity would first be manifested in changed fluorescence intensity levels of GFP-LC3.
Our F MRS method which monitors the uptake of 100% naturally abundant, non-radioactive FDG also detects a combined peak of FDG and FDG-6P, so the primary readout of the two methods shown in Figures 1B and 1C are identical.
That positive results are found in subjects with both quiescent or latent TB and those with active TB confounds all current immune-based assays using interferon-γ expression as the primary readout [28], [29].
These studies have generally used lifespan of population cohorts as a primary readout.
Because these markers appeared to have additive predictive value when used together in the discovery cohort, we made the decision to use the combination (a simple two-marker panel) as the primary readout for the validation.
The primary readouts should focus first on photodynamic efficacy in suspensions, followed by biofilm inactivation (monospecies and polyspecies) in vitro.
The pilots keep an eye on the fuel temperature using an electronic readout in the cockpit.
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