Sentence examples for primary pathological processes from inspiring English sources

In cardiomyopathy with reduced left ventricular ejection fraction, myocardial collagen deposition and AGEs are the primary pathological processes responsible for reduced elasticity of the myocardium in patients with diabetes, whereas increased cardiomyocyte resting tension may be the predominant cause in those with preserved left ventricular ejection fraction (17).

In diabetic cardiomyopathy with reduced LVEF, myocardial collagen deposition and AGEs (advanced glycosylation end-products) are the primary pathological processes responsible for reduced elasticity of the myocardium, whereas increased cardiomyocyte resting tension may be the predominant cause in those cases with preserved LVEF [ 50].

Inflammation is the primary pathological process that precedes the development of BPD.

The primary pathological process in the development of allergic disease is production of immunoglobulin E (IgE).

Autopsy studies show intense sequestration of parasitized erythrocytes in the cerebral microvasculature correlated with coma depth before death [ 8], suggesting that the primary pathological process is microvascular obstruction.

In addition to diseases such as HIV wherein the primary pathological process has an inflammatory component, recent hypotheses suggest that "neuroinflammation" is also causative in the brain damage that occurs in neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases (4, 70, 91).

With severe disruption of P/Q signaling, there appear to be multiple, primary and secondary pathological processes, which can produce ataxia and severely disrupt many aspects of oculomotor performance, or execution, as well as motor learning [1], [2].

Bleomycin hydrolase (BLMH) is a neutral cysteine aminopeptidase that has been ascribed roles in many physiological and pathological processes, yet its primary biological function remains enigmatic.

The vasomotor actions of αCGRP are implied in a variety of both physiological and pathological processes, including migraine and other primary headaches as well as subarachnoidal hemorrhage (SAH) [10, 11].

The model favors endometriosis as an outgrowth of primary cells different in their origin, canalization of pathological processes, manifestation diversity provoked by unique genetic background and epigenetic influences, which result in many different clinical forms of the disease.

Demonstrating BSCB disruption prior to the onset of disease symptoms and other pathological processes would indicate that BSCB disruption plays a primary role in ALS pathogenesis.