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In contrast, the primary pathological feature in CMT type 2 is axonal degeneration.
In axonal forms of Charcot Marie Tooth disease, loss of myelinated axons is the primary pathological feature of the disease, detectable by reduced compound muscle action potential amplitudes.
The increased expression of TRPC3 observed in mdx mouse muscle could therefore be a consequence of ongoing regeneration, rather than a primary pathological feature.
Insulin resistance is a primary pathological feature of type 2 diabetes and predates the onset of diabetes by many years, during which time raised serum insulin levels compensate and maintain normoglycemia.
Similar(56)
The primary clinical and pathological features of AD-ANCL include progressive and widespread neurodegenerative processes resulting in remarkable cortical and cerebellar atrophy [ 5].
Furthermore, p35/Cdk5 was found to suppress the formation of mutant Huntingtin aggregates, a major pathological feature of HD, in primary cultured neurons.
Microhaemorrhages are a well-known pathological feature of schwannomas.
We are exploring aggressive biomaterial-based interventions designed to treat the primary pathological components of AMD.
The other reported the pathological feature of the case of UESL [6].
Lewy bodies are a key pathological feature of PD.
No pathological feature was detected.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com