Sentence examples for primary molecular subtypes from inspiring English sources

Patients were classified into the primary molecular subtypes of MM using the classification proposed by Kumar et al. Molecular classification was assessed by fluorescent in situ hybridization studies in all patients, except one patient in whom the classification of trisomies was made by baseline metaphase cytogenetics that showed hyperdiploidy and trisomies.

Amplification of 12p13 was associated with basal molecular subtype.

PC1 deciphered two primary, intrinsic molecular subtypes of colon cancer that predicted disease progression and recurrence.

Giordano et al (2012) analysed the relationship between CTC and OS in immunohistochemically defined primary tumour molecular subtypes and report that the risk of death increased linearly with increasing CTC counts in all molecular tumour subtypes, but was higher in oestrogen receptor (ER)+ and triple-negative MBC than in HER2+.

Immunohistochemistry was performed on tumour samples using 11 primary antibodies to define five molecular subtypes.

SUVmax of MBC did not correlate with molecular subtypes of primary tumor.

We conclude that while the Baseline SUVmax in our study of MBC did not correlate with molecular subtypes of primary tumor, the SUVmax, rather than molecular subtype, emerged as a potential surrogate marker for survival with metastatic disease.

The distribution of molecular subtypes in primary tumours and corresponding lymph node metastases were compared, and related to 5-year distant disease-free survival (DDFS).

It is indeed remarkable that breast cancer cell lines can be subdivided into the same molecular subtypes as primary cancer [ 16].

In the recently published study from our group [ 22] comparison of molecular subtypes in primary tumour and synchronous lymph node metastases also revealed a shift in individual patients.

The classification according to the St Gallen molecular subtypes in primary tumours and matched lymph node metastases, implicates a shift to a more aggressive subtype in synchronous lymph node metastases compared to the primary breast tumour.