Sentence examples for primary model systems from inspiring English sources

Primary model systems have demonstrated that the pathological expansion of the G4C2 repeat is sufficient to induce neurodegeneration (91).

Cucumber and melon have long served as the primary model systems for sex determination studies due to their diverse floral sex types [ 1].

Both melon and cucumber have diverse floral sex types and have long served as the primary model systems for sex determination studies [ 54].

Neurospora comprises a primary model system for the study of fungal genetics and biology.

As our primary model system for binding and functional killing experiments, we chose the well-characterized ovarian cancer cell line OVCAR3.

Cucumber, Cucumis sativus L., is an economically and nutritionally important crop of the Cucurbitaceae family and has long served as a primary model system for sex determination studies.

To examine whether Mdmx expression promotes the growth of luminal wt p53 BrCa cells, we chose MCF-7 as the primary model system, as it has wt p53 and relatively high Mdmx levels.

Until the late 1990s, yeast was the primary model system for investigating the molecular mechanisms of meiosis [ 4], while flowering plants were only sparingly explored with the exception of cytological studies [ 5, 6].

The discordant results reported here between the effects of miR-16 overexpression in an orthotopic transplant model in immunocompromised mice and miR-16 deletion in a primary tumor model in immunocompetent mice demonstrate the importance of utilizing complementary gain-of-function and loss-of-function approaches and primary tumor model systems for the study of metastasis.

As osteosarcoma xenografts and cell lines still express histological subtype-specific mRNAs that are characteristic of the primary tumor, these model systems are representative for the primary tumor from which they are derived, and will be useful tools for studying mRNA expression and pathways important in high-grade osteosarcoma.

First, the primary tumor model system examined miR-16 deletion.