Two main methodological differences might explain this discrepancy.
These conflicting reports on primary tumor vascularity and prognosis might be due to methodological differences, different study cohort or biological factors [ 6, 19, 20].
One of the primary methodological challenges facing such multisite trials is how to deal with site differences, and variability in treatment effects across sites.
Three primary methodological devices or procedures are at work in Hartshorne's metaphysics.
They deny that the distinction between understanding and explanation points to an important methodological difference.
Consequently, until a method to quantitatively synthesize results has been developed, a sensible qualitative data-synthesis, which takes methodological differences between primary studies into account, is indicated.
Weighted meta-regressions are reported that focus on methodological differences among pooled primary estimates.
This might be explained by methodological differences, like site differences or a different protocol.
25 46 47 48 In addition to containing several more recent studies, our analyses have some key methodological differences that make them more relevant for the primary care population.
Although there were several methodological differences between that study and the present work, we believe that the primary reason for the different conclusions is that the studies were taken under completely different environmental conditions.
