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Computer memory is divided into main (or primary) memory and auxiliary (or secondary) memory.
The development and test environment consists of two Dell PowerEdge 1900 servers, each with two quad core Intel Xeon series 5355 2.66 GHz processors, 4GB of primary memory and a system bus speed of 1333 MHz.
Firstly, common architecture is shared, as the ribonome (RNA space) and the proteome (protein space) are functionally similar to the computer primary memory and the computer cache memory, respectively.
The combination of these algorithmic and technological approaches makes feasible the analysis of large multi-species networks in ordinary computers with limited speed and primary memory and in perspective could enable the analysis of huge networks (e.g. the whole proteomes available in SwissProt), using well-equipped stand-alone machines.
To this end it implements specialized data structures to efficiently break large graphs into small parts that can be quickly loaded into primary memory, and provides efficient disk I/O operations to reduce the number of non sequential accesses to disk.
Our results show that both graph DB technologies (i.e. Neo4j) and secondary memory based systems for graph processing (i.e. GraphChi) can be successfully applied to the analysis of large multi-species networks, even if the latter seems to be less sensitive to the amount of available primary memory, and more efficient for the implementation of network-based algorithms for AFP.
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Major problem in secondary memory access tracing is, involvement of primary memory (main memory) and the semantic gap problem.
High-risk individuals have poorer performance (both accuracy and information processing time) in cognitive tasks reflecting transentorhinal and entorhinal cortical changes and hippocampal reduction as evidenced notably by visuospatial associative learning, spatial analysis and working and primary memory tasks.
Infection or vaccination confers heightened resistance to pathogen rechallenge because of quantitative and qualitative differences between naive and primary memory T cells.
But nothing that happens on Sunday at the stadium is likely to rival my first impression and primary memory of the place.
With a repetitive stimulus the primary memory is simultaneously induced and recalled at successive stimulus episodes but is gated off in between.
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