Sentence examples for primary mediators of from inspiring English sources

Although antibodies are the primary mediators of the protection afforded by most vaccines, T-cell immunity (cell-mediated immunity) can also be detected following administration of routinely administered antigens and may be important in protection.

These regulatory factors (and regulatory RNA) are indeed the primary mediators of the biological response to the environment.

These results reinforce the hypothesis that antioxidants are primary mediators of the conditioning effect.

While most effective vaccines act by eliciting neutralizing antibodies, T cells are the primary mediators of adaptive immunity against TB.

Extensive in vitro experimentation implicates M2 macrophages as the primary mediators of tissue fibrosis, however, the data from in vivo studies present a more complex picture.

Indeed, androgens are known to be the primary mediators of sexual dimorphism in mouse salivary glands.

Serum TNFα and IL-1β levels, two primary mediators of septic shock, are significantly increased in these mice as well.

Thus, these signaling pathways are not primary mediators of cisplatin-induced cell death but rather mirror ongoing cell death.

The small fraction of high affinity EGFR is likely the reason to why its impact is seldom accounted for, even though there are studies proposing that the high-affinity receptors are the primary mediators of the EGFR signaling [17].

This demonstrates that although mice at 3 months of age demonstrate decreased neurofilament staining (Fig. 7B), loss of function in these animals does not progress until cellular infiltration and demyelination occurs, indicating that macrophages are the primary mediators of disease in Tg+ mice.

miRNAs are the primary mediators of the trans-regulation of gene expression [ 22].