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In this study, we have initiated the molecular characterization of Ses, the primary locus controlling the development of Secteurs.
Heteromorphism between the sex-chromosome pair in different lineages was originally proposed as resulting from convergence, whereby presence of the primary locus controlling sex determination on a pair of homologous chromosomes defines a characteristic pattern of differentiation [ 1- 3].
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In the case-control study, the 5q21.2 CNV locus did not show association with high-pressure (≥21 mm Hg) POAG cases.The 5q21.2 CNV locus could represent a novel locus controlling IOP.
The frontal cortex is the primary locus of control; it processes the perceived threat cognitively, and is able to modulate and steer lower levels of neuronal processing ("top-down", [ 7]; see also [ 8, 9]).
The primary locus of control are sub-cortical structures such as the amygdala that activates hypothalamic nuclei that activate the sympathetic autonomic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis.
Anxiety-driven hyper-activity of the hippocampus, which has a central role in cognitive processing and inhibitory functions, may have a central role in disturbed cognition [ 12, 13]. Figure 1 depicts the distinction between fear and anxiety schematically, based on the proximity and specificity of the threatening stimuli, and on the primary locus of control (sub-cortical versus cortical).
The D locus controls sex determination.
Morce, H.C., Shen, F.W. & Hammerling, U. Nomenclature for loci controlling mouse lymphocyte antigens.
Comparative analysis of quantitative trait loci controlling glucosinolates, myrosinase and insect resistance in Arabidopsis thaliana.
Figure 2 shows loci controlling CIA (40 loci) and PGIA (29 loci) in mice [ 65].
No secondary loci were detected in any of the one-dimensional genome scans when controlling for the primary locus that was detected in each analysis.
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