Sentence examples for primary localisation from inspiring English sources
The short range of positrons in tissue necessitates primary localisation of suspected tumour tissue either visually by the surgeon or by using a high-energy gamma detector.
There were no significant differences between groups at baseline in age, tumour size, nodal status, ER or PgR status, histological grade, surgery, primary localisation, prior use of HRT, histological type, chemotherapy, radiotherapy or country.
The relation between bcl-2 protein expression and survival was small, depending on the primary localisation of the tumour (in lymph node of mucosae), and lacked a significant correlation with overall survival.
The following clinical and biological variables were recorded: age, sex, body mass index, primary localisation, sites of metastasis, World Health Organisation (WHO) performance status (PS), Charlson comorbidity score (Charlson et al, 1987), haemoglobin, creatinin clearance (according to Cockroft method), alkaline phosphatase and carcinoembryonic antigen.
In line with the pronounced immunogenicity of MSI-H CRCs, these cancers rarely develop metastases in distant organs and have a comparably good prognosis (Buckowitz et al, 2005; Popat et al, 2005) in spite of a large tumour mass at the primary localisation (Wright et al, 2000).
Primary tumour localisation was gonadal/mediastinal in 12/3 patients.
The Cox regression model included the UGT1A1 genotype, ECOG, sex, age, clinical-risk EORTC classification and primary tumour localisation.
Primary immunocytochemical localisation studies on RAT1 cells suggested that PRMT1 is predominantly nuclear (Tang et al, 1998).
The potential interaction between protein expression and systemic therapy or primary tumour localisation was investigated using Cox regression.
AlexaFluor-488 IgG, AlexaFluor-546 IgG or AlexaFluor-647 secondary IgGs (all from Invitrogen and used at 1 500) were used to reveal primary antibody localisation.
Primary tumour localisation in the colon (P=0.002), a worse WHO performance status at randomisation (P=0.02) and no previous adjuvant chemotherapy (P<0.0001) were more frequently observed in patients with synchronous metastases (Table 1).
